Across TCGA patient cohorts, TMSB4X protein abundance is significantly associated with the RNA expression of many other genes, with 17,756 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TMSB4X-associated genes across cancer lineages are CD4, BTK, and MS4A6A. Each is linked with TMSB4X in more than 6 cancer types. Because this analysis shows association rather than direction, both TMSB4X-to-partner and partner-to-TMSB4X results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMSB4X→partner) and Y-score (partner→TMSB4X) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CD4 →	+0.999	+0.426	<.001	<.001	3	7
UCEC	BTK →	+0.801	+0.564	.001	<.001	3	7
GBM	MS4A6A →	+1.154	+0.344	<.001	.001	3	7
GBM	LY86 →	+0.925	+0.378	.001	<.001	3	7
HNSC	CXorf21 →	+0.987	+0.309	<.001	<.001	3	7
GBM	ALOX5 →	+0.814	+0.312	<.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,756 associations by consensus.

Exploration

TMSB4X survival (RNA) · tumor vs normal (RNA) · all TMSB4X data types