TMSB10

Across TCGA pan-cancer cohorts, TMSB10 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated TMSB10 data layer compared with 25 for mass-spec protein.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher TMSB10 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated TMSB10 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

CCRCC, PDAC, and UCEC are the cancer types where TMSB10 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Tertile	All	0.525	1.000	<.001	31	view →
PDAC	OS	Quartile	All	0.411	0.664	.007	13	view →
UCEC	DFS	Tertile	II,III,IV	0.904	0.429	.018	12	view →
LUAD	OS	Median	All	0.667	0.859	.013	10	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

TMSB10–CCRCC (DFS)

Open the CCRCC breakdown →