TMSB10

Across TCGA pan-cancer cohorts, TMSB10 RNA differs between tumor and matched normal tissue in 15 of 18 cancer types tested, making tumor–normal expression one of TMSB10’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where TMSB10 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TMSB10 is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

KIRC, HNSC, and KIRP are the cancer types where TMSB10 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TMSB10 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	All	+2.341	<.001	12	view →
HNSC	Male	III,IV	+1.701	<.001	12	view →
KIRP	Male	III,IV	+2.344	<.001	11	view →
THCA	Male	III,IV	+1.777	<.001	9	view →
COAD	Female	II,III,IV	+0.799	<.001	9	view →
LIHC	Female	II,III,IV	+2.115	<.001	8	view →
STAD	All	II,III,IV	+1.197	<.001	8	view →
LUAD	All	II,III,IV	+0.667	<.001	8	view →
UCEC	All	All	+1.358	<.001	6	view →
BLCA	All	All	+0.885	.002	6	view →
BRCA	All	All	+0.587	<.001	6	view →
CHOL	Male	All	+4.473	<.001	5	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 15 lineages.

TMSB10–KIRC

Open the KIRC breakdown →