Across TCGA cell cohorts, TMPRSS11F RNA expression is significantly associated with the go_rna of many other GO terms, with 843 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TMPRSS11F-associated GO terms across cancer lineages are Proteasomal ubiquitin-independent protein catabolic process, Regulation of intrinsic apoptotic signaling pathway, and Negative regulation of protein catabolic process. Each is linked with TMPRSS11F in more than 5 cancer types. Because this analysis shows association rather than direction, both TMPRSS11F-to-partner and partner-to-TMPRSS11F results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMPRSS11F→partner) and Y-score (partner→TMPRSS11F) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Proteasomal ubiquitin-independent protein catabolic process →	+0.098	+0.034	.001	.003	3	6
BLOOD_Leukemia	Regulation of intrinsic apoptotic signaling pathway →	+0.028	+0.364	.002	.004	3	6
LUNG_NSCLC_LUSC	Negative regulation of protein catabolic process →	+0.043	+0.084	.008	.005	2	6
LARGE_INTESTINE	Late endosome to vacuole transport →	+0.046	+0.056	.001	.006	3	5
LARGE_INTESTINE	Virion assembly →	+0.057	+0.056	<.001	.006	3	5
KIDNEY	Tail-anchored membrane protein insertion into ER membrane →	+0.061	+0.024	.006	.007	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 843 associations by consensus.

Exploration

TMPRSS11F survival (RNA) · tumor vs normal (RNA) · all TMPRSS11F data types