TMPRSS11D

Across TCGA pan-cancer cohorts, TMPRSS11D mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated TMPRSS11D data layer compared with 22 for mass-spec protein and 11 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher TMPRSS11D mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated TMPRSS11D expression acts as an unfavorable survival marker, although some lineages such as HNSC and LSCC show a favorable association.

HNSC and LSCC are the cancer types where TMPRSS11D mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Tertile	All	1.000	0.929	.013	16	view →
LSCC	DFS	Median	II,III,IV	1.000	0.840	.006	8	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

TMPRSS11D–HNSC (OS)

Open the HNSC breakdown →