TMPRSS11CP

Across TCGA pan-cancer cohorts, TMPRSS11CP RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated TMPRSS11CP data layer.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher TMPRSS11CP RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated TMPRSS11CP expression acts as an unfavorable survival marker, although some lineages such as BLCA and HNSC show a favorable association.

UCEC, BLCA, and UVM are the cancer types where TMPRSS11CP RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Tertile	All	0.865	0.948	<.001	46	view →
BLCA	OS	Quartile	II,III,IV	0.789	0.624	.002	37	view →
UVM	OS	Median	III,IV	0.296	1.000	.005	27	view →
KIRC	DFS	Quartile	All	0.525	0.676	.010	27	view →
HNSC	OS	Median	II,III,IV	0.435	0.283	.011	22	view →
CHOL	DFS	Median	II,III,IV	0.134	0.575	.005	20	view →
PRAD	DFS	Tertile	All	0.656	0.875	.001	14	view →
READ	OS	Median	IV	0.878	0.473	.001	13	view →
PAAD	OS	Tertile	All	0.540	0.351	.024	10	view →
GBM	OS	Quartile	All	0.498	0.346	.033	9	view →
ESCA	DFS	Median	All	0.927	0.509	.026	6	view →
OV	OS	Tertile	IV	0.266	0.512	.009	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

TMPRSS11CP–UCEC (DFS)

Open the UCEC breakdown →