TMPRSS11CP

Across TCGA pan-cancer cohorts, TMPRSS11CP RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of TMPRSS11CP’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where TMPRSS11CP RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TMPRSS11CP is over-expressed in tumor, although a few such as THCA and BRCA show the opposite, repressed pattern.

KIRC, THCA, and STAD are the cancer types where TMPRSS11CP tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TMPRSS11CP RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	III,IV	+0.101	.009	6	view →
THCA	All	II,III,IV	−0.210	.017	5	view →
STAD	Male	III,IV	+0.435	.001	3	view →
CHOL	All	All	+0.475	.002	2	view →
BRCA	All	III,IV	−0.209	.030	2	view →
PRAD	All	All	+0.148	.043	2	view →
LIHC	Female	II,III,IV	+0.137	.018	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

TMPRSS11CP–KIRC

Open the KIRC breakdown →