TMPRSS11BNL

Across TCGA patient cohorts, TMPRSS11BNL RNA expression is significantly associated with the go_rna of many other GO terms, with 6,292 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TMPRSS11BNL-associated GO terms across cancer lineages are Regulation of keratinocyte proliferation, Keratinocyte differentiation, and Autocrine signaling. Each is linked with TMPRSS11BNL in more than 8 cancer types. Because this analysis shows association rather than direction, both TMPRSS11BNL-to-partner and partner-to-TMPRSS11BNL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of keratinocyte proliferation grouped by TMPRSS11BNL-low versus TMPRSS11BNL-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMPRSS11BNL→partner) and Y-score (partner→TMPRSS11BNL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Regulation of keratinocyte proliferation →	+0.062	+1.142	<.001	<.001	3	8
ESCA	Keratinocyte differentiation →	+0.092	+1.753	<.001	<.001	3	8
ESCA	Autocrine signaling →	+0.158	+1.776	<.001	<.001	3	8
ESCA	Keratinocyte proliferation →	+0.069	+1.607	<.001	<.001	3	8
ESCA	Intermediate filament-based process →	+0.075	+1.281	<.001	<.001	3	8
ESCA	Intracellular mRNA localization →	+0.067	+0.903	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,292 associations by consensus.

Regulation of keratinocyte proliferation by TMPRSS11BNL expression — ESCA

Explore this box plot interactively →