Across TCGA patient cohorts, TMPPE protein abundance is significantly associated with the RNA expression of many other genes, with 3,187 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TMPPE-associated genes across cancer lineages are FOLR1, EIF2S1, and RN7SL583P. Each is linked with TMPPE in more than 2 cancer types. Because this analysis shows association rather than direction, both TMPPE-to-partner and partner-to-TMPPE results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMPPE→partner) and Y-score (partner→TMPPE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	FOLR1 →	+1.781	+0.306	<.001	<.001	3	3
GBM	EIF2S1 →	-0.450	-0.350	<.001	<.001	3	3
GBM	RN7SL583P →	-0.657	-0.327	.008	.001	3	2
GBM	FBXO17 →	-0.794	-0.268	.001	.002	3	2
LSCC	ADCK2 →	-0.501	-0.260	.002	.001	3	2
GBM	CYP3A7 →	-0.343	-0.350	.004	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,187 associations by consensus.

Exploration

TMPPE survival (RNA) · tumor vs normal (RNA) · all TMPPE data types