TMPO

Across TCGA cell cohorts, TMPO RNA expression is significantly associated with the go_rna of many other GO terms, with 5,894 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TMPO-associated GO terms across cancer lineages are Regulation of chromosome condensation, DNA-templated DNA replication, and Mitotic sister chromatid cohesion. Each is linked with TMPO in more than 19 cancer types. Because this analysis shows association rather than direction, both TMPO-to-partner and partner-to-TMPO results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of chromosome condensation grouped by TMPO-low versus TMPO-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMPO→partner) and Y-score (partner→TMPO) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Regulation of chromosome condensation →	+0.254	+1.330	<.001	<.001	3	20
OESOPHAGUS	DNA-templated DNA replication →	+0.157	+1.271	<.001	<.001	3	20
OESOPHAGUS	Mitotic sister chromatid cohesion →	+0.190	+1.375	<.001	<.001	3	20
OESOPHAGUS	Immunoglobulin heavy chain V-D-J recombination →	+0.218	+1.036	<.001	<.001	3	20
BONE	DNA replication checkpoint signaling →	+0.251	+1.506	<.001	.001	3	19
OESOPHAGUS	Nuclear chromosome segregation →	+0.159	+1.233	<.001	.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,894 associations by consensus.

Regulation of chromosome condensation by TMPO expression — OESOPHAGUS

Explore this box plot interactively →