TMPO-AS1

Across TCGA pan-cancer cohorts, TMPO-AS1 RNA is linked to patient survival in 27 of 34 cancer types, making it the most broadly survival-associated TMPO-AS1 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher TMPO-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated TMPO-AS1 expression acts as an unfavorable survival marker, although some lineages such as UCS and THYM show a favorable association.

MESO, KIRC, and KICH are the cancer types where TMPO-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Median	All	0.411	0.669	<.001	117	view →
KIRC	OS	Median	All	0.540	0.711	<.001	111	view →
KICH	DFS	Tertile	III,IV	0.125	1.000	<.001	96	view →
LUAD	OS	Tertile	All	0.769	0.883	<.001	86	view →
ACC	DFS	Tertile	All	0.229	0.664	<.001	83	view →
UCS	OS	Quartile	II,III,IV	0.753	0.193	.012	66	view →
KIRP	DFS	Median	All	0.785	0.934	<.001	64	view →
UVM	DFS	Tertile	All	0.246	1.000	.001	60	view →
LIHC	DFS	Tertile	All	0.444	0.654	<.001	48	view →
ESCA	DFS	Median	All	0.388	0.586	.002	43	view →
LGG	OS	Quartile	All	0.690	0.869	<.001	29	view →
PRAD	DFS	Median	All	0.687	0.881	.001	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 27 lineages.

TMPO-AS1–MESO (OS)

Open the MESO breakdown →