Across TCGA cell cohorts, TMLHE RNA expression is significantly associated with the go_rna of many other GO terms, with 3,074 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TMLHE-associated GO terms across cancer lineages are Positive regulation of telomerase RNA localization to Cajal body, Carnitine metabolic process, and scaRNA localization to Cajal body. Each is linked with TMLHE in more than 9 cancer types. Because this analysis shows association rather than direction, both TMLHE-to-partner and partner-to-TMLHE results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMLHE→partner) and Y-score (partner→TMLHE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Positive regulation of telomerase RNA localization to Cajal body →	+0.087	+0.980	.002	.002	3	10
UPPER_AERODIGESTIVE_TRACT	Carnitine metabolic process →	+0.153	+1.201	<.001	<.001	3	10
PANCREAS	scaRNA localization to Cajal body →	+0.078	+0.816	.003	.006	3	9
SOFT_TISSUE	Eosinophil activation involved in immune response →	+0.119	+1.045	<.001	.007	3	9
SOFT_TISSUE	Eosinophil activation →	+0.119	+1.045	<.001	.007	3	9
SOFT_TISSUE	Eosinophil degranulation →	+0.119	+1.045	<.001	.007	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,074 associations by consensus.

Exploration

TMLHE survival (RNA) · tumor vs normal (RNA) · all TMLHE data types