TMF1

Across TCGA patient cohorts, TMF1 mutation is significantly associated with the RNA expression of many other genes, with 4,055 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TMF1-associated genes across cancer lineages are EEF1A1P40, DUXAP3, and RNU6-13P. Each is linked with TMF1 in more than 2 cancer types. Because this analysis shows association rather than direction, both TMF1-to-partner and partner-to-TMF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EEF1A1P40 grouped by TMF1-low versus TMF1-high in KIRP.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMF1→partner) and Y-score (partner→TMF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIRP	EEF1A1P40 →	+0.067	+3.830	.005	.006	3	3
KIRP	DUXAP3 →	+0.189	+4.402	.006	.002	3	3
HNSC	RNU6-13P →	+0.305	+4.025	<.001	.004	3	2
KIRP	SNORA36C →	+0.367	+4.518	<.001	.006	3	2
KIRP	RN7SKP117 →	+0.277	+4.083	.007	.004	3	2
KIRP	BTF3L4P4 →	+0.062	+4.518	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,055 associations by consensus.

EEF1A1P40 by TMF1 expression — KIRP

Explore this box plot interactively →