TMF1

Across TCGA cell cohorts, TMF1 mutation is significantly associated with the RNA expression of many other genes, with 20 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible TMF1-associated genes across cancer lineages are RNASE9, PDYN, and CFC1. Each is linked with TMF1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TMF1-to-partner and partner-to-TMF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNASE9 grouped by TMF1-low versus TMF1-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMF1→partner) and Y-score (partner→TMF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	RNASE9 →	+0.012	+5.209	.001	.005	3	2
OESOPHAGUS	PDYN →	+0.033	+3.392	.006	.007	3	1
OESOPHAGUS	CFC1 →	+0.030	+3.857	<.001	.002	3	1
BLOOD_Lymphoma	DYNAP →	+0.095	+4.867	<.001	.009	3	1
LARGE_INTESTINE	RASGEF1C →	+0.200	+3.404	.007	.006	3	1
BLOOD_Leukemia	OR52M1 →	+0.013	+4.384	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

RNASE9 by TMF1 expression — BLOOD_Lymphoma

Explore this box plot interactively →