TMEM9B

Across TCGA patient cohorts, TMEM9B protein abundance is significantly associated with the RNA expression of many other genes, with 7,114 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible TMEM9B-associated genes across cancer lineages are SUPT3H, NFATC4, and ISYNA1. Each is linked with TMEM9B in more than 3 cancer types. Because this analysis shows association rather than direction, both TMEM9B-to-partner and partner-to-TMEM9B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM9B versus SUPT3H in HNSC, with a Pearson correlation of -0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM9B→partner) and Y-score (partner→TMEM9B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SUPT3H →	-0.700	-0.328	.001	<.001	3	4
CCRCC	NFATC4 →	-0.737	-0.224	<.001	.002	3	3
OV	ISYNA1 →	-1.012	-0.588	.002	.005	3	3
OV	ATP6V0E1 →	+0.789	+0.644	<.001	<.001	3	3
OV	RIOK1 →	-0.449	-0.570	.006	.004	3	3
OV	NASP →	-0.745	-0.629	.003	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,114 associations by consensus.

TMEM9B vs SUPT3H — HNSC

Explore this scatter interactively →