TMEM87B

Across TCGA patient cohorts, TMEM87B protein abundance is significantly associated with the RNA expression of many other genes, with 15,236 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TMEM87B-associated genes across cancer lineages are ZNF653, PSIP1, and SPATA5. Each is linked with TMEM87B in more than 4 cancer types. Because this analysis shows association rather than direction, both TMEM87B-to-partner and partner-to-TMEM87B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM87B versus ZNF653 in OV, with a Pearson correlation of -0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM87B→partner) and Y-score (partner→TMEM87B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ZNF653 →	-0.519	-0.479	<.001	<.001	3	5
BRCA	PSIP1 →	-0.507	-0.333	<.001	.001	3	5
BRCA	SPATA5 →	-0.384	-0.487	.005	<.001	3	5
UCEC	DIPK1B →	-0.847	-0.398	<.001	<.001	3	5
UCEC	SDR39U1 →	-0.490	-0.446	.001	.002	3	4
OV	CABLES1 →	-0.804	-0.445	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,236 associations by consensus.

TMEM87B vs ZNF653 — OV

Explore this scatter interactively →