TMEM87B

Across TCGA cell cohorts, TMEM87B RNA expression is significantly associated with the go_rna of many other GO terms, with 4,838 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TMEM87B-associated GO terms across cancer lineages are Protein catabolic process at synapse, Protein catabolic process at postsynapse, and ERBB signaling pathway. Each is linked with TMEM87B in more than 12 cancer types. Because this analysis shows association rather than direction, both TMEM87B-to-partner and partner-to-TMEM87B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein catabolic process at synapse grouped by TMEM87B-low versus TMEM87B-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM87B→partner) and Y-score (partner→TMEM87B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Protein catabolic process at synapse →	+0.145	+0.925	.004	.009	3	13
STOMACH	Protein catabolic process at postsynapse →	+0.145	+0.925	.004	.009	3	13
OESOPHAGUS	ERBB signaling pathway →	+0.102	+1.236	<.001	.001	3	11
SOFT_TISSUE	Vacuolar transport →	+0.052	+0.919	<.001	.008	3	11
SOFT_TISSUE	Protein targeting →	+0.054	+1.110	<.001	.002	3	11
LIVER	Small GTPase-mediated signal transduction →	+0.070	+1.022	<.001	.004	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,838 associations by consensus.

Protein catabolic process at synapse by TMEM87B expression — STOMACH

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