TMEM87A

Across TCGA patient cohorts, TMEM87A mutation is significantly associated with the RNA expression of many other genes, with 844 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TMEM87A-associated genes across cancer lineages are BPNT2P, HMGB1P45, and RNU6-222P. Each is linked with TMEM87A in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM87A-to-partner and partner-to-TMEM87A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BPNT2P grouped by TMEM87A-low versus TMEM87A-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM87A→partner) and Y-score (partner→TMEM87A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	BPNT2P →	+0.082	+5.758	<.001	.003	3	2
LIHC	HMGB1P45 →	+0.087	+5.268	<.001	.006	3	2
BRCA	RNU6-222P →	+0.219	+4.683	.001	.005	3	2
BRCA	SNRPGP6 →	+0.170	+5.054	<.001	.003	3	2
UCEC	HMGB1P12 →	+0.085	+1.801	.001	.008	3	2
CESC	RNA5SP289 →	+0.202	+4.539	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 844 associations by consensus.

BPNT2P by TMEM87A expression — LIHC

Explore this box plot interactively →