TMEM86B

Across TCGA patient cohorts, TMEM86B mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TMEM86B-associated genes across cancer lineages are CD8+ Tcm and MEP. Each is linked with TMEM86B in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM86B-to-partner and partner-to-TMEM86B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD8+ Tcm grouped by TMEM86B-low versus TMEM86B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM86B→partner) and Y-score (partner→TMEM86B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CD8+ Tcm →	+0.029	+2.935	.009	.013	3	1
UCEC	MEP →	+0.055	+2.839	<.001	.035	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

CD8+ Tcm by TMEM86B expression — UCEC

Explore this box plot interactively →