TMEM86B

Across TCGA cell cohorts, TMEM86B RNA expression is significantly associated with the RNA expression of many other genes, with 9,806 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible TMEM86B-associated genes across cancer lineages are PPP6R1, PPP1R12C, and LY6G5B. Each is linked with TMEM86B in more than 17 cancer types. Because this analysis shows association rather than direction, both TMEM86B-to-partner and partner-to-TMEM86B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM86B versus PPP6R1 in LUNG_NSCLC_LUSC, with a Pearson correlation of 0.73.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM86B→partner) and Y-score (partner→TMEM86B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	PPP6R1 →	+1.149	+1.008	.001	<.001	3	17
LUNG_NSCLC_LUSC	PPP1R12C →	+1.164	+0.995	<.001	<.001	2	18
BONE	LY6G5B →	+1.459	+0.863	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	ZNF865 →	+0.908	+0.669	<.001	<.001	3	14
LUNG_SCLC	IL18BP →	+1.346	+0.876	<.001	.005	3	14
OESOPHAGUS	LENG8 →	+2.018	+0.687	<.001	.001	2	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,806 associations by consensus.

TMEM86B vs PPP6R1 — LUNG_NSCLC_LUSC

Explore this scatter interactively →