TMEM80

Across TCGA patient cohorts, TMEM80 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,554 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TMEM80-associated proteins across cancer lineages are CSTA, CROCC, and PFN1. Each is linked with TMEM80 in more than 4 cancer types. Because this analysis shows association rather than direction, both TMEM80-to-partner and partner-to-TMEM80 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM80 versus CSTA in BRCA, with a Pearson correlation of -0.28.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM80→partner) and Y-score (partner→TMEM80) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CSTA →	-0.775	-0.318	<.001	.006	3	5
OV	CROCC →	+0.244	+0.430	.001	.002	3	4
BRCA	PFN1 →	-0.219	-0.536	<.001	.001	3	4
GBM	NFIA →	+0.507	+0.402	<.001	.001	3	4
GBM	CUL2 →	-0.226	-0.370	.004	.009	3	4
OV	CHORDC1 →	-0.417	-0.525	.001	.006	2	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,554 associations by consensus.

TMEM80 vs CSTA — BRCA

Explore this scatter interactively →