TMEM80

Across TCGA cell cohorts, TMEM80 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,215 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TMEM80-associated GO terms across cancer lineages are Cellular response to methylglyoxal, Response to methylglyoxal, and Methylglyoxal catabolic process. Each is linked with TMEM80 in more than 14 cancer types. Because this analysis shows association rather than direction, both TMEM80-to-partner and partner-to-TMEM80 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular response to methylglyoxal grouped by TMEM80-low versus TMEM80-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM80→partner) and Y-score (partner→TMEM80) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Cellular response to methylglyoxal →	+0.207	+1.265	<.001	<.001	3	15
OESOPHAGUS	Response to methylglyoxal →	+0.207	+1.265	<.001	<.001	3	15
OESOPHAGUS	Methylglyoxal catabolic process →	+0.226	+1.627	<.001	.001	3	15
OESOPHAGUS	Cellular detoxification of methylglyoxal →	+0.207	+1.265	<.001	<.001	3	15
OESOPHAGUS	Methylglyoxal metabolic process →	+0.190	+1.642	<.001	<.001	3	13
OESOPHAGUS	Protein deacylation →	+0.086	+1.052	.002	.005	2	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,215 associations by consensus.

Cellular response to methylglyoxal by TMEM80 expression — OESOPHAGUS

Explore this box plot interactively →