TMEM78

Across TCGA patient cohorts, TMEM78 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,916 significant associations in total. STAD shows the largest number of these associations.

The most reproducible TMEM78-associated GO terms across cancer lineages are RNA methylation, Methylation, and Obsolete ncRNA catabolic process. Each is linked with TMEM78 in more than 26 cancer types. Because this analysis shows association rather than direction, both TMEM78-to-partner and partner-to-TMEM78 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA methylation grouped by TMEM78-low versus TMEM78-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM78→partner) and Y-score (partner→TMEM78) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	RNA methylation →	+0.057	+0.096	<.001	<.001	3	27
STAD	Methylation →	+0.058	+0.117	<.001	<.001	3	26
ESCA	Obsolete ncRNA catabolic process →	+0.056	+0.123	<.001	<.001	3	26
STAD	tRNA modification →	+0.058	+0.097	<.001	<.001	3	26
STAD	Protein acylation →	+0.061	+0.100	<.001	<.001	3	26
ESCA	Regulation of intracellular protein transport →	+0.072	+0.178	<.001	<.001	3	25

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,916 associations by consensus.

RNA methylation by TMEM78 expression — STAD

Explore this box plot interactively →