TMEM78

Across TCGA cell cohorts, TMEM78 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,333 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TMEM78-associated GO terms across cancer lineages are Cilium or flagellum-dependent cell motility, Cilium-dependent cell motility, and Layer formation in cerebral cortex. Each is linked with TMEM78 in more than 6 cancer types. Because this analysis shows association rather than direction, both TMEM78-to-partner and partner-to-TMEM78 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cilium or flagellum-dependent cell motility grouped by TMEM78-low versus TMEM78-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM78→partner) and Y-score (partner→TMEM78) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Cilium or flagellum-dependent cell motility →	-0.081	-0.012	<.001	.006	3	7
URINARY_TRACT	Cilium-dependent cell motility →	-0.081	-0.012	<.001	.006	3	7
STOMACH	Layer formation in cerebral cortex →	+0.175	+0.026	.009	.003	3	7
OVARY	Oxidative demethylation →	-0.180	-0.031	<.001	<.001	3	6
LUNG_NSCLC_LUAD	Response to indole-3-methanol →	+0.127	+0.020	.001	.003	3	6
STOMACH	Sperm motility →	-0.077	-0.039	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,333 associations by consensus.

Cilium or flagellum-dependent cell motility by TMEM78 expression — URINARY_TRACT

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