Across TCGA patient cohorts, TMEM63A RNA expression is significantly associated with the protein abundance of many other proteins, with 14,910 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TMEM63A-associated proteins across cancer lineages are BROX, DDAH1, and PKP4. Each is linked with TMEM63A in more than 6 cancer types. Because this analysis shows association rather than direction, both TMEM63A-to-partner and partner-to-TMEM63A results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM63A→partner) and Y-score (partner→TMEM63A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	BROX →	+0.360	+0.454	<.001	<.001	3	7
HNSC	DDAH1 →	+0.746	+0.697	<.001	<.001	3	6
UCEC	PKP4 →	+0.406	+0.598	<.001	.001	3	6
UCEC	GOLPH3L →	+0.442	+1.013	<.001	<.001	3	5
LUAD	RBM47 →	+0.302	+0.716	<.001	<.001	3	4
LSCC	NUCKS1 →	+0.432	+0.389	.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,910 associations by consensus.

Exploration

TMEM63A survival (RNA) · tumor vs normal (RNA) · all TMEM63A data types