Across TCGA patient cohorts, TMEM63A protein abundance is significantly associated with the RNA expression of many other genes, with 12,931 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TMEM63A-associated genes across cancer lineages are MLPH, ENPP4, and RBM47. Each is linked with TMEM63A in more than 5 cancer types. Because this analysis shows association rather than direction, both TMEM63A-to-partner and partner-to-TMEM63A results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM63A→partner) and Y-score (partner→TMEM63A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	MLPH →	+1.026	+0.435	.001	<.001	3	6
GBM	ENPP4 →	+0.902	+0.260	<.001	<.001	3	6
GBM	RBM47 →	+0.625	+0.297	<.001	<.001	3	6
OV	MANSC1 →	+1.038	+0.581	<.001	<.001	3	5
UCEC	SLC26A8 →	+0.551	+0.694	.008	<.001	3	5
UCEC	CD46 →	+0.822	+0.814	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,931 associations by consensus.

Exploration

TMEM63A survival (RNA) · tumor vs normal (RNA) · all TMEM63A data types