Across TCGA cell cohorts, TMEM63A RNA expression is significantly associated with the RNA expression of many other genes, with 11,717 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible TMEM63A-associated genes across cancer lineages are ARHGAP27, NPIPB5, and RHBDF1. Each is linked with TMEM63A in more than 13 cancer types. Because this analysis shows association rather than direction, both TMEM63A-to-partner and partner-to-TMEM63A results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM63A→partner) and Y-score (partner→TMEM63A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	ARHGAP27 →	+1.755	+1.240	<.001	<.001	3	14
BONE	NPIPB5 →	+1.660	+1.091	<.001	<.001	3	13
BONE	RHBDF1 →	+3.037	+1.367	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	SRRM2 →	+1.397	+1.787	<.001	<.001	3	13
BONE	FBXL8 →	+1.133	+0.991	.001	<.001	3	13
PANCREAS	HOOK2 →	+1.257	+0.903	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,717 associations by consensus.

Exploration

TMEM63A survival (RNA) · tumor vs normal (RNA) · all TMEM63A data types