Across TCGA cell cohorts, TMEM63A RNA expression is significantly associated with the go_rna of many other GO terms, with 4,969 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TMEM63A-associated GO terms across cancer lineages are Cilium movement involved in cell motility, Sperm motility, and Flagellated sperm motility. Each is linked with TMEM63A in more than 14 cancer types. Because this analysis shows association rather than direction, both TMEM63A-to-partner and partner-to-TMEM63A results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM63A→partner) and Y-score (partner→TMEM63A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Cilium movement involved in cell motility →	-0.115	-1.106	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Sperm motility →	-0.114	-0.999	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Flagellated sperm motility →	-0.114	-0.999	<.001	<.001	3	14
OESOPHAGUS	Surfactant homeostasis →	+0.357	+2.213	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Cilium-dependent cell motility →	-0.110	-1.106	<.001	<.001	3	13
URINARY_TRACT	Phospholipid biosynthetic process →	+0.060	+1.274	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,969 associations by consensus.

Exploration

TMEM63A survival (RNA) · tumor vs normal (RNA) · all TMEM63A data types