TMEM62

Across TCGA patient cohorts, TMEM62 protein abundance is significantly associated with the RNA expression of many other genes, with 4,004 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible TMEM62-associated genes across cancer lineages are MARVELD2, PKIA, and GPR156. Each is linked with TMEM62 in more than 2 cancer types. Because this analysis shows association rather than direction, both TMEM62-to-partner and partner-to-TMEM62 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM62 versus MARVELD2 in CCRCC, with a Pearson correlation of 0.30.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM62→partner) and Y-score (partner→TMEM62) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	MARVELD2 →	+0.764	+0.251	<.001	.001	3	3
COAD	PKIA →	-1.394	-0.461	.002	.001	3	3
BRCA	GPR156 →	-0.643	-0.693	<.001	.002	3	3
PDAC	CD163L1 →	-0.701	-0.618	<.001	.003	3	3
HNSC	SPINT1-AS1 →	+0.746	+0.777	.005	.004	3	3
BRCA	RBMS1 →	-0.831	-0.665	.002	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,004 associations by consensus.

TMEM62 vs MARVELD2 — CCRCC

Explore this scatter interactively →