TMEM62

Across TCGA patient cohorts, TMEM62 mutation is significantly associated with the RNA expression of many other genes, with 1,430 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TMEM62-associated genes across cancer lineages are RN7SKP132, ETF1P3, and FTLP14. Each is linked with TMEM62 in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM62-to-partner and partner-to-TMEM62 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP132 grouped by TMEM62-low versus TMEM62-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM62→partner) and Y-score (partner→TMEM62) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SKP132 →	+0.055	+2.761	.003	.009	3	2
UCEC	ETF1P3 →	+0.090	+1.468	.009	.006	3	2
UCEC	FTLP14 →	+0.553	+3.638	.005	.001	3	2
BLCA	RNU11-6P →	+0.184	+3.173	<.001	.009	3	1
BLCA	RPS7P6 →	+0.067	+3.801	.001	<.001	3	1
BLCA	RNU4-86P →	+0.222	+2.786	.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,430 associations by consensus.

RN7SKP132 by TMEM62 expression — UCEC

Explore this box plot interactively →