TMEM59

Across TCGA patient cohorts, TMEM59 RNA expression is significantly associated with the RNA expression of many other genes, with 19,251 significant associations in total. ACC shows the largest number of these associations.

The most reproducible TMEM59-associated genes across cancer lineages are YIPF1, PPCS, and SELENOF. Each is linked with TMEM59 in more than 33 cancer types. Because this analysis shows association rather than direction, both TMEM59-to-partner and partner-to-TMEM59 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM59 versus YIPF1 in ACC, with a Pearson correlation of 0.84.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM59→partner) and Y-score (partner→TMEM59) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ACC	YIPF1 →	+1.105	+0.914	<.001	<.001	3	34
UVM	PPCS →	+1.407	+1.302	<.001	<.001	3	33
UVM	SELENOF →	+1.772	+1.346	<.001	<.001	3	33
ACC	LRRC42 →	+1.314	+0.797	<.001	<.001	3	32
UVM	CTBS →	+1.398	+1.324	<.001	<.001	3	32
UVM	RNF11 →	+1.748	+1.349	<.001	<.001	3	32

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,251 associations by consensus.

TMEM59 vs YIPF1 — ACC

Explore this scatter interactively →