TMEM59

Across TCGA patient cohorts, TMEM59 protein abundance is significantly associated with the protein abundance of many other proteins, with 28,041 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible TMEM59-associated proteins across cancer lineages are KIAA0319L, ITM2B, and PTTG1IP. Each is linked with TMEM59 in more than 6 cancer types. Because this analysis shows association rather than direction, both TMEM59-to-partner and partner-to-TMEM59 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM59 versus KIAA0319L in UCEC, with a Pearson correlation of 0.47.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM59→partner) and Y-score (partner→TMEM59) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	KIAA0319L →	+0.515	+0.492	<.001	.003	2	7
LSCC	ITM2B →	+0.399	+0.347	<.001	<.001	3	5
UCEC	PTTG1IP →	+0.540	+0.439	<.001	<.001	3	4
UCEC	P2RX4 →	+0.811	+0.563	<.001	<.001	3	4
CCRCC	CDCP1 →	+0.685	+0.276	<.001	.001	3	4
HNSC	GPBP1L1_S76 →	+0.497	+0.363	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 28,041 associations by consensus.

TMEM59 vs KIAA0319L — UCEC

Explore this scatter interactively →