TMEM52B

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TMEM52B RNA expression is significantly associated with the protein abundance of many other proteins, with 17,971 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TMEM52B-associated proteins across cancer lineages are RIN3, SKAP2, and HCLS1. Each is linked with TMEM52B in more than 8 cancer types. Because this analysis shows association rather than direction, both TMEM52B-to-partner and partner-to-TMEM52B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM52B versus RIN3 in LSCC, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM52B→partner) and Y-score (partner→TMEM52B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCRIN3 →+0.584+0.948<.001<.00139
OVSKAP2 →+0.794+0.678<.001<.00139
GBMHCLS1 →+0.819+1.120<.001<.00139
UCECNCF2 →+0.659+0.641<.001<.00139
GBMPLCB2 →+0.621+1.014<.001<.00139
GBMRENBP →+0.569+0.846.001<.00138
Each partner links to its Q-omics profile. Showing the 6 strongest of 17,971 associations by consensus.

TMEM52B vs RIN3 — LSCC

Per-sample scatter of TMEM52B vs RIN3 in LSCC (Pearson r = 0.41).

Explore this scatter interactively →

Exploration