TMEM52B

Across TCGA patient cohorts, TMEM52B mutation is significantly associated with the RNA expression of many other genes, with 995 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TMEM52B-associated genes across cancer lineages are TAF13, MIR7702, and RNU6-1133P. Each is linked with TMEM52B in more than 2 cancer types. Because this analysis shows association rather than direction, both TMEM52B-to-partner and partner-to-TMEM52B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TAF13 grouped by TMEM52B-low versus TMEM52B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM52B→partner) and Y-score (partner→TMEM52B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TAF13 →	+0.637	+3.467	.005	.002	3	3
UCEC	MIR7702 →	+0.245	+4.360	<.001	.004	3	2
CESC	RNU6-1133P →	+0.424	+5.669	<.001	.003	3	2
UCEC	VPS37A →	+0.697	+2.711	<.001	.003	3	2
UCEC	KIAA1841 →	+0.664	+2.700	<.001	.006	3	2
UCEC	ATPAF2 →	+0.404	+3.375	.003	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 995 associations by consensus.

TAF13 by TMEM52B expression — UCEC

Explore this box plot interactively →