TMEM52B

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, TMEM52B mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible TMEM52B-associated genes across cancer lineages are TGM7. Each is linked with TMEM52B in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM52B-to-partner and partner-to-TMEM52B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TGM7 grouped by TMEM52B-low versus TMEM52B-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM52B→partner) and Y-score (partner→TMEM52B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_NSCLC_LUADTGM7 →+0.006+4.887<.001.00931
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

TGM7 by TMEM52B expression — LUNG_NSCLC_LUAD

Box plot of TGM7 in TMEM52B-low vs TMEM52B-high samples in LUNG_NSCLC_LUAD.

Explore this box plot interactively →

Exploration