TMEM51

Across TCGA patient cohorts, TMEM51 protein abundance is significantly associated with the RNA expression of many other genes, with 7,383 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible TMEM51-associated genes across cancer lineages are TMEM51-AS1, YWHAZ, and MAFG. Each is linked with TMEM51 in more than 5 cancer types. Because this analysis shows association rather than direction, both TMEM51-to-partner and partner-to-TMEM51 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM51 versus TMEM51-AS1 in PDAC, with a Pearson correlation of 0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM51→partner) and Y-score (partner→TMEM51) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	TMEM51-AS1 →	+0.580	+0.725	<.001	<.001	3	6
LSCC	YWHAZ →	-0.442	-0.316	.001	.007	3	3
LSCC	MAFG →	-0.739	-0.383	<.001	<.001	3	3
GBM	SLC44A1 →	-0.605	-0.313	<.001	<.001	3	3
PDAC	SLC4A4 →	+1.260	+0.449	<.001	<.001	3	3
GBM	JAG1 →	+0.882	+0.369	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,383 associations by consensus.

TMEM51 vs TMEM51-AS1 — PDAC

Explore this scatter interactively →