TMEM50B

Across TCGA patient cohorts, TMEM50B RNA expression is significantly associated with the protein abundance of many other proteins, with 14,681 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible TMEM50B-associated proteins across cancer lineages are EIF3H_S183, IFT46, and N6AMT1. Each is linked with TMEM50B in more than 4 cancer types. Because this analysis shows association rather than direction, both TMEM50B-to-partner and partner-to-TMEM50B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM50B versus EIF3H_S183 in BRCA, with a Pearson correlation of -0.51.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM50B→partner) and Y-score (partner→TMEM50B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	EIF3H_S183 →	-0.626	-0.366	<.001	<.001	3	5
LSCC	IFT46 →	+0.448	+0.428	<.001	.001	3	4
BRCA	N6AMT1 →	+0.323	+0.378	<.001	<.001	3	4
LSCC	PPIF →	-0.477	-0.392	.002	.004	3	4
COAD	UTP20 →	-0.283	-0.517	<.001	<.001	3	4
PDAC	WDR43 →	-0.308	-0.448	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,681 associations by consensus.

TMEM50B vs EIF3H_S183 — BRCA

Explore this scatter interactively →