TMEM50B

Across TCGA patient cohorts, TMEM50B protein abundance is significantly associated with the RNA expression of many other genes, with 95 significant associations in total. OV shows the largest number of these associations.

The most reproducible TMEM50B-associated genes across cancer lineages are HAGHL, CRYM, and ACTR3C. Each is linked with TMEM50B in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM50B-to-partner and partner-to-TMEM50B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM50B versus HAGHL in OV, with a Pearson correlation of 0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM50B→partner) and Y-score (partner→TMEM50B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	HAGHL →	+1.510	+0.548	.002	.004	3	1
OV	CRYM →	-0.346	-0.551	.004	.008	3	1
OV	ACTR3C →	-0.836	-0.605	.001	.001	3	1
OV	SRM →	+0.803	+0.785	.009	.001	3	1
OV	TMED5 →	+0.626	+0.725	.004	.003	3	1
OV	BCL2L12 →	+0.687	+0.631	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 95 associations by consensus.

TMEM50B vs HAGHL — OV

Explore this scatter interactively →