TMEM50B

Across TCGA cell cohorts, TMEM50B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,002 significant associations in total. CNS shows the largest number of these associations.

The most reproducible TMEM50B-associated GO terms across cancer lineages are Glycerophospholipid metabolic process, Vesicle targeting, and Golgi organization. Each is linked with TMEM50B in more than 12 cancer types. Because this analysis shows association rather than direction, both TMEM50B-to-partner and partner-to-TMEM50B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Glycerophospholipid metabolic process grouped by TMEM50B-low versus TMEM50B-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM50B→partner) and Y-score (partner→TMEM50B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Glycerophospholipid metabolic process →	+0.047	+1.026	<.001	<.001	3	13
URINARY_TRACT	Vesicle targeting →	+0.078	+1.075	.004	.001	3	11
OVARY	Golgi organization →	+0.052	+0.696	<.001	.006	3	11
URINARY_TRACT	Glycerolipid biosynthetic process →	+0.052	+1.274	<.001	<.001	3	11
BREAST	Golgi vesicle transport →	+0.065	+0.630	<.001	.001	2	12
URINARY_TRACT	Phospholipid biosynthetic process →	+0.045	+1.180	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,002 associations by consensus.

Glycerophospholipid metabolic process by TMEM50B expression — URINARY_TRACT

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