Across TCGA patient cohorts, TMEM50A RNA expression is significantly associated with the protein abundance of many other proteins, with 9,831 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible TMEM50A-associated proteins across cancer lineages are LUZP1, RPS6KA1, and WDTC1. Each is linked with TMEM50A in more than 5 cancer types. Because this analysis shows association rather than direction, both TMEM50A-to-partner and partner-to-TMEM50A results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM50A→partner) and Y-score (partner→TMEM50A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	LUZP1 →	+0.376	+0.296	<.001	<.001	3	6
GBM	RPS6KA1 →	+0.552	+0.338	<.001	<.001	3	6
OV	WDTC1 →	+0.289	+0.512	.001	<.001	3	5
COAD	NUDC →	+0.385	+0.336	<.001	<.001	3	5
BRCA	LYPLA2 →	+0.316	+0.392	<.001	<.001	3	5
OV	CAPZB →	+0.213	+0.485	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,831 associations by consensus.

Exploration

TMEM50A survival (RNA) · tumor vs normal (RNA) · all TMEM50A data types