Across TCGA patient cohorts, TMEM50A protein abundance is significantly associated with the RNA expression of many other genes, with 2,177 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible TMEM50A-associated genes across cancer lineages are ZDHHC5, CAMSAP1, and CCDC115. Each is linked with TMEM50A in more than 2 cancer types. Because this analysis shows association rather than direction, both TMEM50A-to-partner and partner-to-TMEM50A results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM50A→partner) and Y-score (partner→TMEM50A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	ZDHHC5 →	+0.554	+0.689	<.001	.002	3	2
PDAC	CAMSAP1 →	-0.796	-1.006	.007	.003	3	2
OV	CCDC115 →	-0.764	-0.755	.008	.009	3	2
BRCA	FAM111A →	-1.626	-1.250	<.001	.008	3	2
BRCA	SRR →	-1.366	-1.250	.005	.008	3	2
BRCA	GSTM4 →	-1.076	-1.250	.008	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,177 associations by consensus.

Exploration

TMEM50A survival (RNA) · tumor vs normal (RNA) · all TMEM50A data types