Across TCGA patient cohorts, TMEM50A mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible TMEM50A-associated genes across cancer lineages are MPP, naive B-cells, and mv Endothelial cells. Each is linked with TMEM50A in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM50A-to-partner and partner-to-TMEM50A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM50A→partner) and Y-score (partner→TMEM50A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MPP →	+0.046	+3.510	<.001	.017	3	1
SKCM	naive B-cells →	+0.021	+4.333	.026	.003	3	1
UCEC	mv Endothelial cells →	-0.021	-3.269	.033	.010	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Exploration

TMEM50A survival (RNA) · tumor vs normal (RNA) · all TMEM50A data types