TMEM45B

Across TCGA patient cohorts, TMEM45B RNA expression is significantly associated with the protein abundance of many other proteins, with 15,054 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible TMEM45B-associated proteins across cancer lineages are ARHGAP32, ARHGAP32_S871, and ARHGAP32_S682. Each is linked with TMEM45B in more than 5 cancer types. Because this analysis shows association rather than direction, both TMEM45B-to-partner and partner-to-TMEM45B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM45B versus ARHGAP32 in LUAD, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM45B→partner) and Y-score (partner→TMEM45B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	ARHGAP32 →	+0.317	+1.050	<.001	<.001	3	6
HNSC	ARHGAP32_S871 →	+1.146	+2.073	<.001	<.001	3	6
BRCA	ARHGAP32_S682 →	+0.847	+1.530	<.001	<.001	3	5
HNSC	ARHGAP32_S952 →	+0.757	+2.031	<.001	<.001	3	5
LSCC	ST14 →	+0.551	+1.021	<.001	<.001	3	5
LSCC	BCAS1 →	+1.141	+1.094	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,054 associations by consensus.

TMEM45B vs ARHGAP32 — LUAD

Explore this scatter interactively →