TMEM45B

Across TCGA patient cohorts, TMEM45B protein abundance is significantly associated with the RNA expression of many other genes, with 4,504 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible TMEM45B-associated genes across cancer lineages are SLIT2, BCL2, and RPS6KB2. Each is linked with TMEM45B in more than 2 cancer types. Because this analysis shows association rather than direction, both TMEM45B-to-partner and partner-to-TMEM45B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM45B versus SLIT2 in HNSC, with a Pearson correlation of -0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM45B→partner) and Y-score (partner→TMEM45B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SLIT2 →	-0.866	-0.745	.003	.002	3	3
HNSC	BCL2 →	-0.937	-0.784	.004	.009	3	3
LUAD	RPS6KB2 →	+0.437	+0.693	<.001	.001	3	3
COAD	OLFML1 →	-0.789	-0.384	<.001	.004	3	3
HNSC	TCF4 →	-0.862	-0.899	<.001	<.001	3	3
HNSC	CNFN →	+2.087	+0.964	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,504 associations by consensus.

TMEM45B vs SLIT2 — HNSC

Explore this scatter interactively →