TMEM44

Across TCGA patient cohorts, TMEM44 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,697 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TMEM44-associated proteins across cancer lineages are TMEM44_S472, ARHGEF10L, and SDF2. Each is linked with TMEM44 in more than 5 cancer types. Because this analysis shows association rather than direction, both TMEM44-to-partner and partner-to-TMEM44 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM44 versus TMEM44_S472 in GBM, with a Pearson correlation of 0.59.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM44→partner) and Y-score (partner→TMEM44) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TMEM44_S472 →	+0.690	+0.593	.005	.008	3	6
HNSC	ARHGEF10L →	-0.426	-0.916	<.001	<.001	3	5
LSCC	SDF2 →	+0.394	+0.784	<.001	<.001	3	5
LSCC	MCM2_S41 →	+0.552	+0.730	.001	.002	3	5
OV	PAK2 →	+0.256	+0.683	<.001	.002	3	4
HNSC	PCNA →	+0.427	+0.644	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,697 associations by consensus.

TMEM44 vs TMEM44_S472 — GBM

Explore this scatter interactively →