TMEM44

Across TCGA cell cohorts, TMEM44 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,697 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TMEM44-associated GO terms across cancer lineages are Glycine catabolic process, Glycine decarboxylation via glycine cleavage system, and Sperm motility. Each is linked with TMEM44 in more than 11 cancer types. Because this analysis shows association rather than direction, both TMEM44-to-partner and partner-to-TMEM44 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Glycine catabolic process grouped by TMEM44-low versus TMEM44-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM44→partner) and Y-score (partner→TMEM44) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Glycine catabolic process →	-0.249	-1.224	.002	.001	2	12
UPPER_AERODIGESTIVE_TRACT	Glycine decarboxylation via glycine cleavage system →	-0.249	-1.224	.002	.001	2	12
UPPER_AERODIGESTIVE_TRACT	Sperm motility →	-0.117	-1.095	<.001	<.001	2	10
BREAST	Cellular response to water stimulus →	+0.138	+1.381	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Flagellated sperm motility →	-0.117	-1.095	<.001	<.001	2	10
BONE	Response to water →	+0.147	+1.045	.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,697 associations by consensus.

Glycine catabolic process by TMEM44 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →