TMEM41B

Across TCGA patient cohorts, TMEM41B protein abundance is significantly associated with the RNA expression of many other genes, with 7,267 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible TMEM41B-associated genes across cancer lineages are RAB33A, CMKLR1, and RNF125. Each is linked with TMEM41B in more than 3 cancer types. Because this analysis shows association rather than direction, both TMEM41B-to-partner and partner-to-TMEM41B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM41B versus RAB33A in UCEC, with a Pearson correlation of -0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM41B→partner) and Y-score (partner→TMEM41B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RAB33A →	-0.754	-0.776	.003	.004	3	3
HNSC	CMKLR1 →	-0.872	-0.443	.003	<.001	3	3
BRCA	RNF125 →	-0.528	-0.567	.002	.002	3	3
BRCA	ETS1 →	-0.651	-0.645	.001	.006	2	4
CCRCC	IL17RD →	-0.642	-0.309	<.001	<.001	3	3
BRCA	SYNE3 →	-0.473	-0.569	.006	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,267 associations by consensus.

TMEM41B vs RAB33A — UCEC

Explore this scatter interactively →