TMEM39B

Across TCGA cell cohorts, TMEM39B RNA expression is significantly associated with the RNA expression of many other genes, with 12,603 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TMEM39B-associated genes across cancer lineages are SRSF4, PSRC1, and SNRNP40. Each is linked with TMEM39B in more than 17 cancer types. Because this analysis shows association rather than direction, both TMEM39B-to-partner and partner-to-TMEM39B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM39B versus SRSF4 in SOFT_TISSUE, with a Pearson correlation of 0.63.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM39B→partner) and Y-score (partner→TMEM39B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	SRSF4 →	+1.077	+0.798	<.001	<.001	3	18
SOFT_TISSUE	PSRC1 →	+1.369	+0.773	<.001	<.001	3	16
KIDNEY	SNRNP40 →	+1.184	+1.047	<.001	<.001	3	16
LUNG_SCLC	IQCC →	+1.064	+0.806	<.001	<.001	3	15
BREAST	GMEB1 →	+0.903	+1.125	<.001	<.001	3	15
BLOOD_Myeloma	SFPQ →	+1.068	+0.881	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,603 associations by consensus.

TMEM39B vs SRSF4 — SOFT_TISSUE

Explore this scatter interactively →