TMEM38B

Across TCGA cell cohorts, TMEM38B mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible TMEM38B-associated genes across cancer lineages are IL17F, FTMT, and PRAMEF19. Each is linked with TMEM38B in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM38B-to-partner and partner-to-TMEM38B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IL17F grouped by TMEM38B-low versus TMEM38B-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM38B→partner) and Y-score (partner→TMEM38B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	IL17F →	+0.071	+4.930	<.001	.008	3	1
SOFT_TISSUE	FTMT →	+0.086	+5.977	<.001	.001	3	1
SOFT_TISSUE	PRAMEF19 →	+0.030	+5.977	<.001	.001	3	1
LARGE_INTESTINE	ELOA3DP →	+0.021	+4.273	.009	.006	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

IL17F by TMEM38B expression — SOFT_TISSUE

Explore this box plot interactively →