TMEM37

Across TCGA cell cohorts, TMEM37 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,058 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TMEM37-associated GO terms across cancer lineages are Aerobic respiration, Cellular respiration, and ATP synthesis coupled electron transport. Each is linked with TMEM37 in more than 12 cancer types. Because this analysis shows association rather than direction, both TMEM37-to-partner and partner-to-TMEM37 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Aerobic respiration grouped by TMEM37-low versus TMEM37-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM37→partner) and Y-score (partner→TMEM37) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Aerobic respiration →	+0.075	+0.732	<.001	<.001	3	13
URINARY_TRACT	Cellular respiration →	+0.065	+0.870	<.001	.001	3	13
BONE	ATP synthesis coupled electron transport →	+0.080	+1.744	<.001	.002	3	12
BONE	Mitochondrial ATP synthesis coupled electron transport →	+0.080	+1.744	<.001	.002	3	12
LIVER	Aerobic electron transport chain →	+0.086	+2.539	.007	.009	3	12
LIVER	ATP biosynthetic process →	+0.082	+2.601	.008	.007	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,058 associations by consensus.

Aerobic respiration by TMEM37 expression — URINARY_TRACT

Explore this box plot interactively →